Safety
Slim Metrix Side Effects: What to Watch For
Slim Metrix side effects come from its ingredients, and most reported ones are mild.
They include stomach upset, sweating, nausea and poor sleep; liver injury from green tea extract is rare. Some ingredients can add to diabetes drugs or change other drugs. It is not meant for pregnancy, breastfeeding or anyone under 18.
Written by the Slim Metrix editorial teamUpdated
Ingredient by ingredient
What are the side effects of Slim Metrix?
Nobody has published a study of Slim Metrix side effects. What we know comes from research on its ten ingredients, listed below in label order.
Most reported problems are mild. The serious ones are rare: liver injury, low blood sugar on top of diabetes medicine, and harm to newborns. Eight ingredients share one 276 mg blend with no single amounts (Slim Metrix label graphic), so nobody can say how much of each you swallow.
| Ingredient | What sources report |
|---|---|
| Zinc | Too much over time lowers copper; the adult limit is 40 mg a day from all sources (NIH ODS: zinc fact sheet). |
| Alpha-lipoic acid | Nausea, vomiting and low blood sugar (MSK About Herbs: alpha-lipoic acid). |
| Green tea extract | A rare but well-established cause of liver injury, usually 1 to 6 months after starting (LiverTox: green tea). |
| Milk thistle | Stomach upset; allergic reactions in people allergic to ragweed-family plants (NCCIH: milk thistle). |
| Chromium, berberine, resveratrol | Mainly drug interactions (see the medicines table below); berberine can also harm newborns (MSK About Herbs: berberine). |
| Cayenne | Sweating and stomach irritation (MSK About Herbs: cayenne). |
| Korean ginseng | Trouble sleeping is the most common; may interfere with blood clotting (NCCIH: Asian ginseng). |
| Banaba | Little safety research; one kidney-injury case report (Miura et al.: banaba and corosolic acid (review)). |
No cinnamon row: it is not in the formula. See the Supplement Facts, typed out.
Liver
Can Slim Metrix cause liver damage?
It could, but it would be rare. Green tea extract, one of the eight blend ingredients, is a well-established cause of liver injury, with more than 100 published cases (LiverTox: green tea).
Cases usually showed up 1 to 6 months after starting. Europe's food safety agency saw liver enzymes rise at 800 mg of EGCG a day or more (EFSA: safety of green tea catechins).
Had liver trouble before? Ask your doctor first, and ask which warning signs to watch for. More on the green tea extract page.
Interactions
Which medicines interact with Slim Metrix?
Diabetes medicines, transplant drugs, blood thinners and some antibiotics top the list. Show this table to your pharmacist.
| If you take | Ingredient to ask about | Why |
|---|---|---|
| Insulin, metformin or other diabetes medicine | Chromium, alpha-lipoic acid, Korean ginseng | Chromium may add to the glucose-lowering effect of insulin or metformin; alpha-lipoic acid can add to diabetes medicines; ginseng might lower blood sugar. Lows mean a reading below 70 mg/dL. (NIH ODS: chromium fact sheet) (MSK About Herbs: alpha-lipoic acid) (NCCIH: Asian ginseng) (NIDDK: low blood glucose) |
| Metformin | Berberine | In one study, goldenseal extract, a berberine-containing herb, lowered metformin levels by about 25 percent. (NCCIH: goldenseal and berberine) |
| Cyclosporine or tacrolimus (transplant drugs) | Berberine, cayenne | Berberine may raise their levels; capsaicin may raise cyclosporine levels. (MSK About Herbs: berberine) (MSK About Herbs: cayenne) |
| Medicines broken down by CYP2D6, CYP2C9 or CYP3A4 (many common drugs) | Berberine, resveratrol | Berberine lowered these enzymes' activity in people; resveratrol changed them at 1 g a day. Ask a pharmacist which of your drugs use them. (MSK About Herbs: berberine) (MSK About Herbs: resveratrol) |
| Warfarin and other blood thinners | Resveratrol, Korean ginseng, milk thistle | Resveratrol may raise bleeding risk; ginseng may interfere with clotting; milk thistle may interact with warfarin. (MSK About Herbs: resveratrol) (NCCIH: Asian ginseng) (MSK About Herbs: milk thistle) |
| Sirolimus | Milk thistle | Milk thistle may interact with sirolimus. (MSK About Herbs: milk thistle) |
| Nadolol (a beta blocker) | Green tea | High doses of green tea lowered nadolol blood levels. (NCCIH: green tea) |
| Blood pressure medicines | Cayenne | Capsaicin may affect blood pressure drugs and may add to the cough some ACE inhibitors cause. (MSK About Herbs: cayenne) |
| Quinolone or tetracycline antibiotics | Zinc | Zinc can reduce how well these antibiotics are absorbed. (NIH ODS: zinc fact sheet) |
| A prescription GLP-1 or other weight-loss medicine | The whole formula | Not studied together. Tell every prescriber about every supplement you take. (NCCIH: using dietary supplements wisely) |
The table lists only interactions a cited source states. Other combinations are unstudied, not proven safe. Tell every doctor and pharmacist about each supplement you take.
Blood sugar
Can Slim Metrix cause low blood sugar?
It can, mainly if you take insulin, a sulfonylurea or other glucose-lowering medicine. Three of its ingredients may add to the effect of those drugs.
Chromium may add to insulin or metformin (NIH ODS: chromium fact sheet). Alpha-lipoic acid can add to diabetes medicines and lists low blood sugar as a side effect (MSK About Herbs: alpha-lipoic acid). Korean ginseng might lower blood sugar too.
- A low is usually a reading below 70 mg/dL, with shakiness, hunger or dizziness (NIDDK: low blood glucose).
- Never cut a prescribed medicine to make room for a supplement.
Skip it or ask first
Who should not take Slim Metrix?
Do not take it if you are pregnant, breastfeeding or under 18. Four other groups should ask a doctor first; see who it suits.
Pregnant or breastfeeding
Berberine can harm newborns and may worsen infant jaundice (MSK About Herbs: berberine). Cayenne should be avoided then too.
Under 18
The label graphic gives directions for adults only.
Transplant patients
Berberine and cayenne may raise cyclosporine levels; berberine may raise tacrolimus too.
Cancer treatment
Alpha-lipoic acid may counteract chemotherapy or radiation.
Ragweed or daisy allergy
Milk thistle can trigger allergic reactions.
Kidney disease
Banaba's one kidney-injury report was in a person with weak kidneys.
If something feels off
What should I do if Slim Metrix gives me a side effect?
Stop taking it and call your doctor or pharmacist. If symptoms are severe, get urgent care.
Stop the capsules
Stopping is the simplest test.
Bring the bottle to your doctor
Show all ten ingredients, not the six named in ads, and say when you started.
Ask about your liver
Green tea injury tends to appear in the first six months, so ask whether a blood test makes sense.
Call about a refund
Within 60 days, call +1 (855) 482-1597 with your order ID.
What the label skips
Does the Slim Metrix label have a safety warning?
No. The brand's Supplement Facts graphic shows no caution panel, no storage line and no company name (Slim Metrix label graphic).
The sales page footer is the only place we found safety advice: see a physician first if you are pregnant, nursing, on medication or living with a medical condition (Sales page, quickslimstep.com/frt).
FAQ
Slim Metrix side effect questions
Does Slim Metrix have caffeine?
The label does not say. It lists a green tea leaf extract standardized to polyphenols, catechins and EGCG, but gives no caffeine amount. Green tea naturally contains caffeine (NCCIH: green tea), so if you are sensitive to it, ask the order desk whether the extract is decaffeinated before you order.
Can Slim Metrix upset my stomach?
It can. Milk thistle can cause stomach upset, cayenne can irritate the stomach, and alpha-lipoic acid can cause nausea (MSK About Herbs: cayenne). If your stomach stays upset, stop the capsules and tell your doctor or pharmacist what you took and when it started.
Can Slim Metrix keep me awake at night?
It might. Trouble sleeping is the most common side effect of Korean ginseng (NCCIH: Asian ginseng), and the label does not say whether the green tea extract holds caffeine. Taking the capsule in the morning, as the label graphic suggests, is the simplest way to lower the chance.
Is Slim Metrix suitable in pregnancy or while breastfeeding?
No. Berberine can harm newborns and may worsen infant jaundice, so it should not be used in pregnancy or breastfeeding (NCCIH: goldenseal and berberine). Cayenne should be avoided at those times as well. If you are trying to get pregnant, skip it and talk with your doctor.
Can I take Slim Metrix if I have kidney disease?
Ask your kidney doctor first. Banaba has little safety research, and one case report linked its corosolic acid to kidney injury in a person whose kidneys were already weak and who also took diclofenac (Miura et al.: banaba and corosolic acid (review)). One report is not proof, but it is reason enough to ask.
Is it safe to take Slim Metrix with Ozempic or Wegovy?
No one has studied that combination. Slim Metrix is not a GLP-1 drug, and several of its ingredients may add to glucose-lowering medicines. Tell the doctor who prescribes your GLP-1 medicine before you add any supplement, and never use one in place of the other.
Who wrote this
Written and reviewed by
Plain-language pages built from the brand's label graphic, the sales page and linked medical sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a U.S. stocking partner for Slim Metrix, not by the manufacturer. We earn money when you buy through our order links.
Keep reading
More about Slim Metrix
Green tea extract
Green tea extract in Slim Metrix: the EGCG math, the small weight effect and the rare liver risk.
Read moreBerberine
Berberine in Slim Metrix: why one capsule cannot reach a studied dose, and who should skip it.
Read more
Who it's for
A quick fit check: who Slim Metrix suits, who should ask a doctor first, and who should skip it.
Read moreU.S. stocking partner for Slim Metrix
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